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Raphaëlle Chaix

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Researcher CNRS
Evolutionary Anthropology group (UMR 7206)

Musée de l’Homme
17, place du Trocadéro
75016 Paris
tel : +

Current research field

Interactions between biological (genetic and epigenetic) processes and cultural processes in human evolution

Main projects

- Project SoGen From social to genetic structures : a genome-wide approach in South-East Asia (funded by ANR)

- Project EpiMed Influence of the meditative practice on the human epigenome (funded by PEPS INEE)

- Project MHCmate Influence of the MHC (Major Histocompatibility Complex) on mate choice in humans (funded by MNHN)

Dandine-Roulland C, Laurent R, Dall’Ara I, Toupance B, Chaix R. Genomic evidence for MHC disassortative mating in humans Proceedings of the Royal Society B, 286 : 20182664.

Ly G, Alard B, Laurent R, Lafosse S, Toupance B, Monidarin ., … Chaix R (2018). Residence rule flexibility and descent groups dynamics shape uniparental genetic diversities in South East Asia. Am J of Phys Anthr, 165 (3) : 1–12.

Chaix R, Alvarez-López MJ, Fagny M, Lemee L, Regnault B, Davidson RJ, … Kaliman P (2017). Epigenetic clock analysis in long-term meditators. Psychoneuroendocr, 85(May) : 210–214.

Aimé C, Laval G, Patin E, Verdu P, Ségurel L, Chaix R, Hegay T, Quintana-Murci L, Heyer E, Austerlitz F. Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming. Mol Biol Evol 2013 Dec ;30(12):2629-44

Heyer E, Chaix R, Pavard S., Austerlitz F (2012) Sex-specific behaviors that shape human genomic variation Molecular Ecology Feb ;21(3):597-612

Laurent R, Chaix R (2012) HapMap European American genotypes are compatible with the hypothesis of MHC-dependent mate choice : response to Derti and Roth Bioessays 34 : 871–872

Laurent R, Chaix R (2012). MHC-dependent mate choice in humans : why genomic patterns from the HapMap data support the hypothesis. Bioessays 34 : 267–271

Laurent R, Toupance B, Chaix R (2012) Non-random mate choice in humans : insights from a genome scan Molecular Ecology 21(3) : 587–596

Heyer E, Balaresque P, Jobling MA, Quintana-Murci L, Chaix R, Segurel L, Aldashev A, Hegay T (2009) Genetic diversity and the emergence of ethnic groups in Central Asia. BMC Genetics 10:49

Chaix R, Somel M, Kreil DP, Khaitovich P, Lunter G (2008) Evolution of Primate Gene Expression : Drift and Corrective Sweeps ? Genetics 180:1379 - 1389

Chaix R, Austerlitz F, Khegay T, Quintana-Murci L, Heyer E. (2008) Genetic traces of east to west expansion waves in Eurasia. American Journal of Physical Anthropology 136(3):309-317

Chaix R, Cao C, Donnelly P (2008) Is mate choice in humans MHC-dependent ? PLoS Genet 4:e1000184

Chaix R, Quintana-Murci L, Hegay T, Hammer M, Mobasher Z, Austerlitz F, [Heyer E-291] (2007) From social to genetic structures in Central Asia. Current Biology 17 : 43-48

McVean G, Spencer C, Chaix R (2005) Perspectives on human genetic variation from the HapMap project. Plos Genetics 1:413-418

Kalaydjieva L, Morar B, Chaix R, Tang H (2005) A newly discovered founder population : the Roma/Gypsies. Bioessays 27:1084-1094

Thackeray JF, Maureille B, Vandermeersch B, Braga J, Chaix R (2005) Morphometric comparisons between Neanderthals and ’anatomically modern’ Homo sapiens from Europe and the Near East. Annals of the Transvaal Museum 42:47-51

Chaix R, [Austerlitz F-519], Khegay T, Jacquesson S, Hammer MF et al. (2004) The Genetic or Mythical Ancestry of Descent Groups : Lessons from the Y Chromosome. Am J Hum Genet 75(6):1113-1116.

Chaix R, Austerlitz F, Morar B, Kalaydjieva L, [Heyer E-291] (2004) Vlax Roma history : what do coalescent-based methods tell us ? Eur J Hum Genet 12(4) : 285-292.

Quintana-Murci L, Chaix R, Wells RS, Behar DM, Sayar H et al. (2004) Where west meets east : the complex mtDNA landscape of the southwest and Central Asian corridor. Am J Hum Genet 74(5) : 827-845.

Scientific popularization
Co-author of the scientific documentary Espèces d’Espèces (2009)